Human Photo-Energetic Transduction

Redox implications of AMPK-mediated signal transduction beyond energetic clues.

Since the discovery of AMP-dependent protein kinase (AMPK), its fundamental role in regulating metabolic pathways and the molecular mechanism underlying the regulation of its activity by adenine nucleotides has been widely studied. AMPK is not only an energy-responsive enzyme, but it also senses redox signals. This review aims at recapitulating the recent lines of evidence that demonstrate the ...

Drosophila Photo-transduction Simulator – Journal of Open Research Software

This software contains detailed modelling of the single photon response, the quantum bump, of fly photoreceptors. All known components participating in the primary phototransduction process are taken into account, and estimates are given for both the physical and chemical parameters. Both deterministic and stochastic simulations of the photoinduced current are possible using the same software. ...

Signal amplification and transduction by photo-activated catalysis.

A simple flavin-based catalytic system is able to transform light into chemical output with amplified response utilizing a Cu(I)-catalyzed cycloaddition reaction.

Effect of photo–electron therapy on human neoplastic cells

Background: Cancer is a complex disease with high rate of mortality. At present, Radiation therapy is one of the most common procedures to overcome this situation. The deficiency of conventional method is the lack of fatal dose transmission into the malignant tissue. Hence, uncertain dose may cause regeneration of cancer cells, and relapse of the disease and invasion of the cancer cells to ...

Signal Transduction and Human Disease